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Test Code ZMMLSM Antimicrobial Susceptibility, Aerobic Bacteria, MIC

Infectious

Additional Codes

LAB15828

Methodology

Minimum Inhibitory Concentration (MIC) by Agar Dilution

Performing Laboratory

St. Mary's Regional Medical Center-Microbiology

Specimen Requirements

Culture isolate. Antimicrobial agent appropriate to the organism and specimen source will be chosen from the panels listed below.

 

Antibiotic/organism combination reported according to CLSI standards.

 

Gram-negative bacillus: amikacin, ampicillin, ampicillin/sulbactam, aztreonam, cefazolin, cefepime, cefotaxime, cefotoxitin, ceftazidime, ceftriaxone, ciprofloxacin, doripenem, ertapenem, gentamicin,   nitrofurantoin, piperacillin/tazobactam, tigecycline, tobramycin, and trimethoprim/ sulfamethoxazole. Screening and confirmation tests for extended spectrum beta-lactamases are performed for Escherichia coli and Klebsiella species isolates. Screening for carbapenemase resistance is performed on all isolates of Enterobacteriaceae. If positive, KPC molecular testing and modified Hodge testing are added and billed as confirmatory tests. If susceptibilities have already been performed, KPC molecular testing and/or modified Hodge are available for individual order.

 

Staphylococcus species:  ampicillin, augmentin, ciprofloxacin, clindamycin, daptomycin, erythromycin, gentamicin, levofloxacin, linezolid, *nitrofurantoin, oxacillin, penicillin, tetracycline, TMP/SMX, and vancomycin.

 

Enterococcus species: ampicillin, ciprofloxacin, daptomycin, gentamicin synergy, levofloxacin, linezolid, *nitrofurantoin, penicillin, streptomycin synergy, and vancomycin.

 

Streptococcus species: dependent upon species

 

* for urine only

 

For antimicrobial agents not part of above: testing is available upon special request at an additional charge per antimicrobial.

 

Note: Organism identification and specimen source are required.

Reference Values

Results reported as MIC in µg/mL and as susceptible, intermediate, or resistant (according to the CLSI guidelines)

Day(s) Test Set Up

Monday through Sunday